Mechanisms and Models in Rheumatoid Arthritis

Rheumatoid arthritis is a bewilderingly complex disease involving the interactions of many, and varied, cell populations and multiple families of low and high molecular mass mediators. We are only slowly beginning to understand the mechanisms that produce the local and systematic pathology clinically recognized as rheumatoid arthritis. Increasingly, use is being made of experimental models of this disease in an effort to test hypotheses about putative pathological mechanisms and to investigate the effect of novel therapeutic agents. A major section of this book covers these experimental models in great detail from their development through to reviews of the most recent information on each model.Mechanisms and Models in Rheumatoid Arthritis brings together a group of eminent researchers from the fields of clinical rheumatology, pathology, experimental pathology, immunology, connective tissue biochemistry, microbiology, pharmacology and developmental biology to describe the current views of the cellular and humoral mechanisms that drive the pathology of rheumatoid arthritis and experimental models of rheumatoid arthritis.

Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases

Focuses on the role of bioactive foods in mediating the riskof arthritis and other inflammatory tissue diseases.

Encyclopedia of Women and Gender, Two-Volume Set

The study of gender differences began in earnest in the 1970s and has since increased dramatically to infiltrate virtually all fields of study in the social and behavioral sciences. Along the way, it was discovered that while women very often think and behave differently than do men, industrialized societies cater to masculine perspectives. The “Psychology of Women” emerged as a field of study focusing on just those areas in which women most often butted against assumed roles. And similarly, in the 1990s, the “Psychology of Men” emerged to focus on the same issues for men.The Encyclopedia of Gender covers all three areas under one cover, discussing psychological differences in personality, cognition, and behavior, as well as biologically based differences and how those differences impact behavior. Coverage includes studies of these differences in applied settings such as education, business, the home, in politics, sports competition, etc.

The Career Psychology of Women

Summarizing literature from the twenty-year-old field of women’s career development, this book brings scholars and professionals up-to-date in their understanding of the factors influencing women’s career choices and career adjustment across the life span. It serves as a vital base for theoretical and empirical work in the study of women’s career development.

Women and Health, 2nd Edition

An unparalleled and valuable compendium of data for anyone interested in women’s health.” — THE NEW ENGLAND JOURNAL OF MEDICINE

Headache

This volume is part of the Handbook of Clinical Neurology series, the worlds most comprehensive source of information in neurology. Now in its third generation, the series has an unparalleled reputation for providing the latest foundational research, diagnosis, and treatment protocols essential for both basic neuroscience research and clinical neurology.

Pain and Touch

An explosion of advances in the area of tactile perception and pain led to the development of this comprehensive, state-of-the-art text on basic research and clinical practice. Equal parts psychology and neuroscience, Pain and Touch covers peripheral cutaneous tactile information processing, sensory mapping, tactile exploratory behavior, neurophysiology of nociception and nociceptors in pain research, clinical scaling methods for psychophysics of pain, and paincontrol, pathology, and therapeutics.

Chronic Pain and Brain Abnormalities

The only reference on the market to adequately explore long-term changes in the brain resulting from chronic pain

Placebo and Pain

The definitive reference linking pain and the placebo effect, from basic science to clinical implications

Asthma, 3rd Edition

Now available in its Third Edition, Asthma: Basic Mechanisms and Clinical Management has become the reference text in asthma. This highly successful text sheds new light on the basic physiological and molecular mechanisms of asthma, how current treatments work, and how best to apply the latest knowledge to control this important disease. The Third Edition has undergone radical revision and includes several new chapters. It retains the virtues of the previous volumes by bringing together all of the recent research findings by internationally recognized experts on the causative mechanisms of asthma, including in-depth clinical aspects and therapy. The book presents an integrated approach toward the treatment of this disease with new concepts, changes in asthma management, and the development of new therapeutic agents. Asthma provides extensive references for researchers and clinicians who need to keep abreast of recent developments in this rapidly expanding field.

Asthma and COPD

Chronic obstructive pulmonary disease (COPD), which encompasses both chronic bronchitis and emphysema, is one of the most common respiratory conditions of adults in the developed world. Asthma and COPD: Basic Mechanisms and Clinical Management provides a unique, authoritative comparison of asthma and COPD. Written and edited by the world’s leading experts, it is a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments.

Asthma and COPD, 2nd Edition

Offers a truly translational presentation of airway diseases “ from bench to bedside “ illuminating the mechanisms, etiology, and pathogenesis of respiratory disease and then translating how these mechanisms affect patient conditions, treatment options, and effective therapies.

Asthma and Allergic Diseases

This book updates the previous coverage of the mechanisms and mediators of asthma and its treatment. It presents articles by the foremost names in the field.

T-Lymphocyte and Inflammatory Cell Research in Asthma

It is well established that asthma is an inflammatory disease of the airway mucosa and drugs like inhaled glucocorticoids are now commonly introduced early in therapy. A characteristic feature of this disease is the vast number of eosinophils in airway tissue, although many other migratory and resident inflammatory cells with the capacity to synthesize and release cytokines and putative asthma mediators are present in the inflamed mucosa. The cross-talk between lymphocytes and these cells and the role of cytokines in complex biological networks are currently areas of intense research.This volume gathers together chapters and discussions on the biology of immunocompetent and inflammatory cells, cellular interplay and communication, and on the relative importance of cells and mediators in disease.It should help contribute to further insights into the pathology of asthma and to the development of novel efficacious drugs for the treatment of asthma and related respiratory disorders.