New England Journal of Medicine


The New England Journal of Medicine ( is dedicated to bringing physicians the best research and key information at the intersection of biomedical science and clinical practice, and to presenting the information in an understandable and clinically useful format. A career companion for physicians, NEJM keeps practicing physicians informed on developments that are important to their patients and keeps them connected to both clinical science and the values of being a good physician.

NEJM employs a highly rigorous peer-review and editing process to evaluate manuscripts for scientific accuracy, novelty, and importance. The editors have set policies to ensure that authors disclose all relevant financial associations and that those financial associations do not influence published content. These factors contribute to NEJM’s reputation as the “gold standard” for quality biomedical research and for the best practices in clinical medicine.

NEJM is the most widely read, cited, and influential general medical periodical in the world. As it evolves to meet the changing needs of its readers in the 21st century, it is committed to maintaining that reputation and integrity, while using innovative formats and technologies for new features and faster delivery and access.


The New England Journal of Medicine is the oldest continuously published medical periodical, completing its second century of service to the medical community in 2012.

In 1811, John Collins Warren, a Boston physician and scholar, collaborated with his colleague, James Jackson, to establish the first medical journal in New England. The first quarterly edition of the New England Journal of Medicine and Surgery and the Collateral Branches of Medical Science was published in Boston in January 1812. Sixteen years later, after merging with the Boston Medical Intelligencer, it became the Boston Medical and Surgical Journal, and weekly publication began. The Massachusetts Medical Society purchased it in 1921 for $1. In 1928, it was renamed the New England Journal of Medicine.

NEJM has published reports from the frontiers of medical science and practice since its early days. NEJM documented the first public demonstration of ether anesthesia in 1846, the first full description of a spinal-disk rupture in 1934, and the first successes in the treatment of early childhood leukemia in 1948. More recent articles include some of the earliest descriptions of AIDS and then of its treatment, of aspirin and cholesterol-lowering agents in the prevention of heart disease, and of new molecular advances in the treatment of chronic leukemia and lung cancer.


NEJM’s influence has grown to an international scale. More than 600,000 people in 177 countries read it each week. More than half of the research reports submitted to NEJM originate from outside the U.S. NEJM is cited more often in scientific literature than any other medical journal, and in 1978, became the only American medical journal ever to receive the Polk Award for journalistic merit. Free online access is available in more than 100 low-income countries, and full text of research articles is free to all six months after publication. was created in 1996, and now more people see NEJM articles online than in print.

NEJM launched a new website along with the full NEJM Archive in 2010. The new website gives users a deeper, broader, and more engaging experience through enhanced search and navigation, specialty pages, interactive elements, and a number of integrated multimedia features. Through the NEJM Archive, every article published in NEJM since 1812 — a rich history of modern medicine — is available and completely searchable online.

In 2012, NEJM Group was formed, a division of the Massachusetts Medical Society (MMS) that produces the New England Journal of Medicine and Journal Watch.